Principal Proposed Uses:
Isoflavones are naturally occurring, hormonally active substances found in soy and other foods. Chemical modifications of isoflavones have been studied as possible alternative treatments for various conditions. One of these, ipriflavone , was developed primarily for treating osteoporosis . Methoxyisoflavone is a chemical derivative of ipriflavone, but it is marketed as a bodybuilding aid .
Methoxyisoflavone is not a nutrient and is not supplied to any meaningful extent in food. However, it is possible that, once in the body, natural isoflavones, such as daidzein, may be converted to some extent into methoxyisoflavone.
A typical recommended dose of methoxyisoflavone is 200 mg to 400 mg taken twice daily.
Methoxyisoflavone is marketed as an anabolic steroid, said to increase muscle mass without causing androgenic (testosterone-like) effects. However, there is no meaningful evidence that it actually works.
Another oft-repeated claim regarding methoxyisoflavone is that it is widely utilized in the livestock industry to enhance lean mass. However, if livestock breeders are in fact using methoxyisoflavone, they are keeping it quiet: an Internet search for “methoxyflavone” and “livestock” turned up numerous sites that sell supplements to humans (and make this claim to support the sales of their product), but not a single site by or for livestock breeders.
The bottom line: There is no meaningful evidence to indicate that methoxyisoflavone is useful as a sports supplement .
Methoxyflavone has not undergone comprehensive safety testing. Those who take it do so at their own risk.
- Reviewer: EBSCO CAM Review Board
- Review Date: 09/2014 -
- Update Date: 09/18/2014 -