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Methazolamide

Methazolamide 

En Español (Spanish Version)

(meth'' a zol' a mide)

WHY is this medicine prescribed?

Methazolamide is used to treat glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision). Methazolamide is in a class of medications called carbonic anhydrase inhibitors. It works by decreasing the pressure in the eye.

HOW should this medicine be used?

Methazolamide comes as a tablet to take by mouth. It is usually taken two or three times a day. Take methazolamide at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take methazolamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Methazolamide controls glaucoma but does not cure it. Continue to take methazolamide even if you feel well. Do not stop taking methazolamide without talking to your doctor.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What SPECIAL PRECAUTIONS should I follow?

Before taking methazolamide,

  • tell your doctor and pharmacist if you are allergic to methazolamide, sulfa drugs, any other medications, or any of the ingredients in methazolamide tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: aspirin; oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone); and vitamins. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had liver, kidney, or adrenal gland disease. Your doctor may tell you not to take methazolamide.
  • tell your doctor if you have or have ever had lung disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking methazolamide, call your doctor.
  • you should know that methazolamide may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Methazolamide may make your skin sensitive to sunlight.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Methazolamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • pain, burning, or tingling in the hands or feet
  • hearing problems or ringing in the ears
  • tiredness or lack of energy
  • vomiting or diarrhea
  • change in how things taste
  • increased urination
  • vision changes

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

  • blisters or peeling skin

• hives

• rash

• itching

  • difficulty breathing or swallowing
  • fever, sore throat, chills, and other signs of infection
  • unusual bruising or bleeding
  • muscle weakness
  • seizures

• nausea

  • extreme tiredness
  • loss of appetite
  • pain in the upper right part of the stomach
  • yellowing of the skin or eyes
  • flu-like symptoms

Methazolamide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What should I do in case of OVERDOSE?

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to methazolamide.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand Names

  • Neptazane®[¶]
  • Also available generically

This branded product is no longer on the market. Generic alternatives may be available.

Medication Information

The information contained in this tool is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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