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March 2013 Briefing - Hematology & Oncology

March 2013 Briefing - Hematology & Oncology

Hormone Therapy Ups Breast Cancer Risk, Mortality

FRIDAY, March 29 (HealthDay News) -- Postmenopausal hormone therapy with estrogen plus progestin is associated with an increased risk of breast cancer, according to a study published online March 29 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/21/jnci.djt043.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/21/jnci.djt043.full )Editorial (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/21/jnci.djt058.extract )

Multiple Strategies Are More Efficient for Cervical Cancer

FRIDAY, March 29 (HealthDay News) -- Multiple cervical cancer screening strategies that maximize early detection of high-grade disease without excessive increases in initial testing appear to be most effective, according to a study published in the March issue of the American Journal of Obstetrics & Gynecology.

Abstract (http://www.ajog.org/article/S0002-9378(12)02075-3/abstract )Full Text (subscription or payment may be required) (http://www.ajog.org/article/S0002-9378(12)02075-3/fulltext )

Metabolite-Based Test May Detect Early Pancreatic Cancer

FRIDAY, March 29 (HealthDay News) -- A test that measures four serum metabolites can accurately distinguish patients with pancreatic cancer from healthy people and patients with pancreatitis, according to a study published online March 29 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract (http://cebp.aacrjournals.org/content/early/2013/03/27/1055-9965.EPI-12-1033.abstract )Full Text (subscription or payment may be required) (http://cebp.aacrjournals.org/content/early/2013/03/27/1055-9965.EPI-12-1033.full.pdf+html )

Many Uninsured Vets Will Be Eligible for Medicaid Under ACA

FRIDAY, March 29 (HealthDay News) -- A large proportion of uninsured veterans and their spouses will be eligible for Medicaid or new subsidies for coverage under the Affordable Care Act (ACA), according to a report published by the Robert Wood Johnson Foundation.

More Information (http://www.rwjf.org/content/dam/farm/reports/issue_briefs/2013/rwjf405143 )

Viral DNA-Based Testing Can Triage Women With Abnormal Pap

THURSDAY, March 28 (HealthDay News) -- DNA-based testing with Hybrid Capture 2 (HC2) assay is more accurate than repeat cytology in identifying women with cervical cancer when their initial Pap smear shows atypical squamous cells of undetermined significance (ASCUS), according to research published online March 28 in The Cochrane Library.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008054.pub2/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008054.pub2/full )

Study: Primary Care Extension Program Should Be Funded

THURSDAY, March 28 (HealthDay News) -- The Primary Care Extension Program (PCEP) has the potential to transform primary care and needs to be funded, according to a study published in the March/April issue of the Annals of Family Medicine.

Abstract (http://annfammed.org/content/11/2/173.abstract )Full Text (subscription or payment may be required) (http://annfammed.org/content/11/2/173.full )

Using Internet Search Logs Can Help Identify Drug Interactions

THURSDAY, March 28 (HealthDay News) -- Search logs can be used to inexpensively mine for anonymized signals that may alert authorities to potential drug interactions and add new Web-scale pharmacovigilance capabilities, according to research published online March 6 in the Journal of the American Medical Informatics Association.

Abstract (http://jamia.bmj.com/content/early/2013/02/05/amiajnl-2012-001482.abstract )Full Text (subscription or payment may be required) (http://jamia.bmj.com/content/early/2013/02/05/amiajnl-2012-001482.full.pdf+html )

Cell-Cycle Progression Panel Identifies Prostate Cancer Risk

THURSDAY, March 28 (HealthDay News) -- The cell-cycle progression (CCP) gene panel is useful to improve the risk stratification for men with even low-risk, clinically localized prostate cancer, according to research published online March 4 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.46.4396.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.46.4396.full.pdf+html )

Regional Variation Noted in Prevalence of Delayed Care

THURSDAY, March 28 (HealthDay News) -- There is considerable county-wide variation in the prevalence of delayed care, with high prevalence linked to a weaker health care infrastructure, according to a letter published in the March 28 issue of the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMc1214874 )

Inpatient Deaths Fell by 8 Percent in Last Decade

WEDNESDAY, March 27 (HealthDay News) -- The number of inpatient hospital deaths declined by 8 percent over the last decade, although the total number of hospitalizations increased by 11 percent during the same period, according to a March data brief issued by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

Full Text (http://www.cdc.gov/nchs/data/databriefs/db118.htm )

Weight Loss, Muscle Depletion May Predict Cancer Survival

WEDNESDAY, March 27 (HealthDay News) -- Cancer patients with high weight loss, low muscle index, and low muscle attenuation have a poor prognosis regardless of body mass index (BMI), according to a study published online March 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.45.2722.abstract?sid=7d429274-7dd2-4e6f-b20e-fcb3ae02af94 )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.45.2722.full.pdf+html?sid=da40cfa2-827f-416e-b931-5e9aceb76ffc )

Smoking Has Gender-Specific Effect in Urothelial Carcinoma

WEDNESDAY, March 27 (HealthDay News) -- For patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU), the impact of smoking is gender specific, with worse outcomes for females than for males, according to a study published online March 6 in BJU International.

Abstract (http://onlinelibrary.wiley.com/doi/10.1111/bju.12014/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1111/bju.12014/full )

Genetic Susceptibility Loci ID'd for Leukemia in Children

WEDNESDAY, March 27 (HealthDay News) -- For children, inherited genetic variants correlate strongly with susceptibility to acute lymphoblastic leukemia (ALL), according to a study published online March 19 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt042.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt042.full )

Submitting Peer-Review Reports Could Expedite Process

WEDNESDAY, March 27 (HealthDay News) -- Attaching previous peer-review reports during the next submission of the same paper to a different journal could optimize the peer-review process, according to research published in the March/April issue of the Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/179.abstract?sid=830532ac-da58-4c89-87ca-b0c3ee2f8ffc )Full Text (http://www.annfammed.org/content/11/2/179.full )Editorial (http://www.annfammed.org/content/11/2/104.full?sid=48707c4b-ebf8-4a86-b8b0-726cf918c1ed )

Early Baldness Ups Prostate CA Risk for African-Americans

TUESDAY, March 26 (HealthDay News) -- For African-Americans, who are at elevated prostate cancer risk, baldness at age 30 correlates with prostate cancer, with frontal baldness linked to increased odds of high-stage and high-grade disease, according to a study published online March 26 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract (http://cebp.aacrjournals.org/content/early/2013/03/22/1055-9965.EPI-12-0944.abstract )Full Text (subscription or payment may be required) (http://cebp.aacrjournals.org/content/early/2013/03/22/1055-9965.EPI-12-0944.full.pdf+html )

Risk of Prostate Cancer Quantified for Lynch Syndrome

TUESDAY, March 26 (HealthDay News) -- Lynch syndrome carriers have about a two-fold increased risk of prostate cancer, according to a study published online March 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.44.1238.abstract )Full Text (http://jco.ascopubs.org/content/early/2013/03/21/JCO.2012.44.1238.full.pdf+html )

Residency Reforms Reduced Duty Hours, Increased Sleep

TUESDAY, March 26 (HealthDay News) -- Additional residency reforms implemented in 2011 have reduced duty hours and increased sleep duration, but with perceived reductions in quality of patient care, according to research published online March 25 in JAMA Internal Medicine.

Abstract - Sen (http://archinte.jamanetwork.com/article.aspx?articleid=1672284#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1672284 )Abstract - Desai (http://archinte.jamanetwork.com/article.aspx?articleid=1672279#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1672279 )

Unintended Harmful Effects of Mammography Studied

TUESDAY, March 26 (HealthDay News) -- A false-positive test result from screening mammography is not harmless and can result in negative long-term psychosocial consequences, according to research published in the March/April issue of the Annals of Family Medicine.

Abstract (http://www.annfammed.org/content/11/2/106.abstract )Full Text (http://www.annfammed.org/content/11/2/106.full )

Even the Poorest Handheld Umbrellas Can Block UV Rays

MONDAY, March 25 (HealthDay News) -- Handheld umbrellas are effective at blocking ultraviolet radiation (UVR), according to a study published online March 20 in JAMA Dermatology.

Full Text (subscription or payment may be required) (http://archderm.jamanetwork.com/article.aspx?articleid=1670412 )

Gene Variants in RGS Linked to Bladder Cancer Outcomes

MONDAY, March 25 (HealthDay News) -- For patients with bladder cancer, genetic variants in the regulator of G-protein signaling (RGS) pathway are associated with risk, recurrence, progression, and death, according to a study published online March 25 in Cancer.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27871/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27871/full )

Engineered Immune Cells Lead to Leukemia Remission

FRIDAY, March 22 (HealthDay News) -- Five patients with relapsed B cell acute lymphoblastic leukemia (B-ALL) quickly achieved complete remission after treatment with autologous engineered T cells, according to research published in the March 20 issue of Science Translational Medicine.

Abstract (http://stm.sciencemag.org/content/5/177/177ra38.abstract )Full Text (subscription or payment may be required) (http://stm.sciencemag.org/content/5/177/177ra38.full )

No Overall Survival Benefit Tied to Bilateral Oophorectomy

FRIDAY, March 22 (HealthDay News) -- At no age is there an overall survival benefit associated with bilateral oophorectomy compared with ovarian conservation at the time of hysterectomy for benign disease, according to a study published online March 6 in Obstetrics & Gynecology.

Abstract (http://journals.lww.com/greenjournal/Abstract/publishahead/Long_Term_Mortality_Associated_With_Oophorectomy.99867.aspx )Full Text (subscription or payment may be required) (http://journals.lww.com/greenjournal/Abstract/publishahead/Long_Term_Mortality_Associated_With_Oophorectomy.99867.aspx )

Mobility Impaired May Have Difficulty Accessing Docs

FRIDAY, March 22 (HealthDay News) -- Many U.S. subspecialty practices cannot accommodate patients with mobility impairment, according to a study published in the March 19 issue of the Annals of Internal Medicine.

Full Text (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1667265 )Editorial (subscription or payment may be required) (http://annals.org/article.aspx?articleID=1667280 )

Better Long-Term Outcomes With Low Hep C Viral Load

FRIDAY, March 22 (HealthDay News) -- In patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), low HCV viral load predicts better long-term surgical outcomes, regardless of the serologic eradication of HCV, according to research published in the Feb. 20 issue of the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/31/6/766.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/31/6/766.full )

Impact of Budget Sequestration on Health Care Discussed

THURSDAY, March 21 (HealthDay News) -- The impact of sequestration will have far-reaching consequences in health care, according to a perspective piece published online March 20 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1303266?query=featured_home )

ERCC1 Not Effective for Guiding Therapeutic Decisions

THURSDAY, March 21 (HealthDay News) -- Currently available antibodies for the excision repair cross-complementation group 1 (ERCC1) protein are not adequate for therapeutic decision-making regarding the potential efficacy of cisplatin-containing treatment in patients with non-small-cell lung cancer, according to a study published the March 21 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1214271 )

Heart-Healthy Lifestyle Can Also Reduce Cancer Risk

THURSDAY, March 21 (HealthDay News) -- Subjects who are enrolled in the Atherosclerosis Risk in Communities (ARIC) study and are meeting goals for six to seven ideal health metrics have a 51 percent lower risk of incident cancer than those not meeting any goals for ideal health metrics, according to research published online March 18 in Circulation.

Abstract (http://circ.ahajournals.org/content/early/2013/03/13/CIRCULATIONAHA.112.001183.abstract )Full Text (http://circ.ahajournals.org/content/early/2013/03/13/CIRCULATIONAHA.112.001183.full.pdf+html )

Effect of Immigration Status on Medicaid Eligibility Discussed

WEDNESDAY, March 20 (HealthDay News) -- Under the Affordable Care Act, a considerable proportion of low-income uninsured adults will be ineligible for Medicaid coverage due to their immigration status, and their main providers are likely to be safety-net health care providers, according to a March report published by the State Health Access Data Assistance Center.

More Information (http://www.rwjf.org/en/research-publications/find-rwjf-research/2013/03/state-estimates-of-the-low-income-uninsured-not-eligible-for-the.html )

Sepsis Drug Eritoran Not Superior to Placebo

TUESDAY, March 19 (HealthDay News) -- Eritoran, a synthetic analog of lipid A and a toll-like receptor 4 antagonist, is no better than placebo in reducing mortality in patients with severe sepsis, according to a study published in the March 20 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1669798#Abstract )Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1669798 )

ER Discharge Dx/Disposition Discordant With Chief Complaint

TUESDAY, March 19 (HealthDay News) -- A considerable proportion of patients with emergency department visits with the same presenting complaint as those ultimately given a primary care-treatable diagnosis require immediate emergency care or hospital admission, according to a study published in the March 20 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1669818#Abstract )Full Text (http://jama.jamanetwork.com/article.aspx?articleid=1669818 )Editorial (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1669802 )

Variation Seen in Vena Cava Filter Use Among Hospitals

TUESDAY, March 19 (HealthDay News) -- The frequency of vena cava filter (VCF) use in patients with acute venous thromboembolism (VTE) varies widely and depends primarily on hospital practice, even after adjustment for clinical and socioeconomic factors, according to research published online March 18 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1669098#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1669098 )

Conflict-of-Interest Disclosures Common at 2011 AAOS Meeting

TUESDAY, March 19 (HealthDay News) -- At the 2011 American Academy of Orthopaedic Surgeons (AAOS) annual meeting, voluntarily disclosed conflicts of interest were common, especially for featured symposia, according to a study published in the March 6 issue of The Journal of Bone & Joint Surgery.

Abstract (http://jbjs.org/article.aspx?articleid=1654958 )Full Text (subscription or payment may be required) (http://jbjs.org/article.aspx?articleid=1654958 )

Older Women Can Safely Undergo Mammography Biennially

MONDAY, March 18 (HealthDay News) -- Women 50 to 74 years old can safely undergo mammography every two years instead of annually, while women 40 to 49 years old should only undergo annual mammography if they have extremely dense breasts, according to a study published online March 18 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1669103#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1669103 )

Evidence Indicates Link for Shift Work, Ovarian Cancer

MONDAY, March 18 (HealthDay News) -- Shift work may be associated with an increased risk of ovarian cancer, according to a study published in the April issue of Occupational & Environmental Medicine.

Abstract (http://oem.bmj.com/content/70/4/231.short?g=w_oem_current_tab )Full Text (subscription or payment may be required) (http://oem.bmj.com/content/70/4/231.full )Editorial (subscription or payment may be required) (http://oem.bmj.com/content/70/4/283.extract )

Final Rule in Notice of Benefit, Payment Parameters Issued

FRIDAY, March 15 (HealthDay News) -- The final rule of the Department of Health and Human Services (HHS) Notice of Benefit and Payment Parameters for 2014, which expands on existing standards, has been released.

More Information (http://content.govdelivery.com/bulletins/gd/USCMS-6ebb0f )

Oral Melatonin Has No Effect on Appetite in Advanced Cancer

FRIDAY, March 15 (HealthDay News) -- Oral melatonin does not improve appetite, weight, or quality of life for patients with cachexia due to advanced cancer, according to research published online Feb. 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.43.6766.short?rss=1 )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.43.6766.full.pdf+html )Editorial (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.48.3149.full.pdf+html )

Health Insurance Exchanges Will Mainly Be Run by Feds

FRIDAY, March 15 (HealthDay News) -- More than half of the states within the United States will allow the federal government to establish health insurance exchanges, according to a report issued by the Henry J. Kaiser Family Foundation.

More Information (http://www.statehealthfacts.org/comparemaptable.jsp?ind=962&cat=17 )

Primary Health Risks Outweigh Long-Term Radiation Concerns

FRIDAY, March 15 (HealthDay News) -- Immediate health risks supersede lifetime radiation-induced cancer risk in patients undergoing computed tomography (CT) surveillance for testicular cancer, according to a study published in the March issue of Radiology.

Abstract (http://radiology.rsna.org/content/266/3/896.abstract?sid=6007d871-71db-4878-b169-2e49cff5f33b )Full Text (subscription or payment may be required) (http://radiology.rsna.org/content/266/3/896.full )

High-Fat Dairy Linked to All-Cause, Breast Cancer Mortality

FRIDAY, March 15 (HealthDay News) -- For women with a breast cancer diagnosis, high-fat dairy consumption is associated with a higher mortality risk, according to a study published online March 14 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt027.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt027.full )Editorial (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt052.extract )

Stimulated Reporting Accounts for High Dabigatran Bleeding

THURSDAY, March 14 (HealthDay News) -- The increased number of post-marketing reports of bleeding associated with use of dabigatran seems to be an example of stimulated reporting and may not represent an increased bleeding risk, according to a perspective piece published online March 13 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1302834?query=featured_home )

Family-Centered Advanced Care Planning Benefits Ailing Teens

THURSDAY, March 14 (HealthDay News) -- Family-centered advanced care planning (ACP) enables families to better understand and agree on end-of-life decisions for adolescents with cancer, according to a study published online March 11 in JAMA Pediatrics.

Abstract (http://archpedi.jamanetwork.com/article.aspx?articleid=1663080#Abstract )Full Text (subscription or payment may be required) (http://archpedi.jamanetwork.com/article.aspx?articleid=1663080 )

Medicare Cancer Spending Has Little Effect on Survival

THURSDAY, March 14 (HealthDay News) -- Medicare spending for advanced cancer care has substantial regional variation, according to a study published online March 12 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt025.abstract )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/03/08/jnci.djt025.full )

Medicare Patients Enrolled in Hospice Receive Better Care

THURSDAY, March 14 (HealthDay News) -- Medicare patients who enroll in hospice care receive better care at a lower cost, with the greatest savings if they enroll 15 to 30 days before death, according to a study published in the March issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/3/552.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/3/552.full )

Geriatric Factors Can Foretell Tolerances to Chemotherapy

THURSDAY, March 14 (HealthDay News) -- For elderly patients with metastatic colorectal cancer (mCRC), scores on the Mini-Mental State Examination (MMSE) and Instrumental Activities of Daily Living (IADL) were predictive of severe toxicity or unexpected hospitalization after fluorouracil-based chemotherapy with or without irinotecan (IRI), according to research published online March 4 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.42.9894.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.42.9894.full.pdf+html )

Circulating Tumor DNA Is Key Clue to Breast Cancer Spread

THURSDAY, March 14 (HealthDay News) -- Circulating tumor DNA is a better biomarker of metastatic breast cancer than cancer antigen 15-3 (CA 15-3) or circulating tumor cells, according to a study published online March 13 in the New England Journal of Medicine.

Abstract (http://www.nejm.org/doi/full/10.1056/NEJMoa1213261 )Full Text (http://www.nejm.org/doi/full/10.1056/NEJMoa1213261#t=article )Editorial (http://www.nejm.org/doi/full/10.1056/NEJMe1301249 )

FDA Approves Lymphoseek to Help Locate Lymph Nodes

WEDNESDAY, March 13 (HealthDay News) -- The injected imaging drug Lymphoseek (technetium Tc 99m tilmanocept) has been approved by the U.S. Food and Drug Administration to help surgeons locate the lymph nodes among people with breast cancer or melanoma who are undergoing surgery to remove tumor-draining lymph nodes.

More Information (http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm343525.htm )

Incidental Exposure of Heart to Radiation Ups Cardiac Events

WEDNESDAY, March 13 (HealthDay News) -- For women who receive radiotherapy for breast cancer, incidental exposure of the heart is associated with an increased risk of major coronary events, according to a study published in the March 14 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1209825 )Editorial (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMe1215300 )

AMA Files Brief Contesting Insurer's Payment Practices

WEDNESDAY, March 13 (HealthDay News) -- A landmark case examining the question of whether physicians can bring a class arbitration against a health insurer who has underpaid them is currently before the U.S. Supreme Court, in a brief filed by the Litigation Center of the American Medical Association and State Medical Societies and the Medical Society of New Jersey.

More Information (http://www.ama-assn.org/ama/pub/physician-resources/legal-topics/litigation-center.page? )

Psycho-Oncologic Interventions May Be Beneficial for Adults

TUESDAY, March 12 (HealthDay News) -- For adults with cancer, psycho-oncologic interventions, such as relaxation, individual and group psychotherapy, and psychoeducation, may be effective in producing significant small-to-medium improvement in patients' emotional distress and quality of life, according to a study published in the Feb. 20 issue of the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/31/6/782.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/31/6/782.full.pdf+html )

$120 Million to Be Sequestered From Health Centers in 2013

TUESDAY, March 12 (HealthDay News) -- Budget sequestration, which is expected to reduce federal spending, is likely to result in a $120 million loss in grant funding for the nation's 1,200 community health centers in 2013, according to a report published by the Geiger Gibson/ RCHN Community Health Foundation Research Collaborative.

More Information (http://sphhs.gwu.edu/departments/healthpolicy/publications/GGRCHN.pdf )

Many Elderly Consider Cancer Screening Obligatory

TUESDAY, March 12 (HealthDay News) -- Many older adults consider cancer screening to be morally obligatory, but screening colonoscopy is often given inappropriately in the elderly, according to two studies published online March 11 in JAMA Internal Medicine.

Abstract - Torke (http://archinte.jamanetwork.com/article.aspx?articleid=1666431#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1666431 )Abstract - Sheffield (http://archinte.jamanetwork.com/article.aspx?articleid=1666433#Abstract )Full Text (http://archinte.jamanetwork.com/article.aspx?articleid=1666433 )Editorial (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1666436 )

Aspirin Cuts Melanoma Risk in Postmenopausal Caucasians

MONDAY, March 11 (HealthDay News) -- For postmenopausal Caucasian women, aspirin use is associated with a significantly reduced risk of melanoma, according to a study published online March 11 in Cancer.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27817/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/cncr.27817/full )

Processed Meat Consumption Linked to Higher Mortality Risk

MONDAY, March 11 (HealthDay News) -- Processed meat consumption is linked to an increased risk of mortality, according to a study published in the March issue of BMC Medicine.

Abstract (http://www.biomedcentral.com/1741-7015/11/63/abstract )Full Text (http://www.biomedcentral.com/1741-7015/11/63 )

Three Biomarkers Accurately Detect Kidney Cancer

MONDAY, March 11 (HealthDay News) -- Measuring the levels of three serum proteins can detect kidney cancer with high accuracy, according to a study published in the March issue of Cancer Epidemiology, Biomarkers & Prevention.

Abstract (http://cebp.aacrjournals.org/content/22/3/390.abstract )Full Text (subscription or payment may be required) (http://cebp.aacrjournals.org/content/22/3/390.full )

Shelf Life of Blood Appears Shorter Than Thought

FRIDAY, March 8 (HealthDay News) -- Red blood cells stored longer than three weeks begin to lose their flexibility, according to a small study published online Feb. 28 in Anesthesia & Analgesia.

Abstract (http://www.anesthesia-analgesia.org/content/early/2013/02/27/ANE.0b013e31828843e6.abstract?sid=4c4b6ed8-c103-4f21-983c-959eda016078 )Full Text (subscription or payment may be required) (http://www.anesthesia-analgesia.org/content/early/2013/02/27/ANE.0b013e31828843e6.full.pdf+html )

PTSD Symptoms Common After Breast Cancer Diagnosis

FRIDAY, March 8 (HealthDay News) -- Following a diagnosis of breast cancer, nearly one-quarter of women report symptoms of posttraumatic stress disorder (PTSD), according to a study published online Feb. 21 in the Journal of the National Cancer Institute.

Abstract (http://jnci.oxfordjournals.org/content/early/2013/02/21/jnci.djt024.abstract?sid=b506bcc9-51f3-473b-afdd-8dd5e181eac6 )Full Text (subscription or payment may be required) (http://jnci.oxfordjournals.org/content/early/2013/02/21/jnci.djt024.full )

Circulatory System Mortality Declining in Hodgkin's

FRIDAY, March 8 (HealthDay News) -- Among patients treated for Hodgkin's lymphoma (HL), long-term excess mortality due to diseases of the circulatory system (DCS) is expected to continue to decline, according to research published online Feb. 25 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.45.2714.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/02/25/JCO.2012.45.2714.full.pdf+html )

FSH, Inhibin B Poor Predictors of Sperm Count After Cancer

THURSDAY, March 7 (HealthDay News) -- Serum levels of follicle-stimulating hormone (FSH) and inhibin B are not good predictors of sperm levels in male survivors of childhood cancer, according to a study published online Feb. 19 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/02/19/JCO.2012.43.7038.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/02/19/JCO.2012.43.7038.full.pdf+html )

MicroRNAs May Define Advance of Barrett's Esophagus

THURSDAY, March 7 (HealthDay News) -- A series of microRNAs has been identified that differentiate precancerous Barrett's esophagus from esophageal adenocarcinoma and may serve as biomarkers to help physicians identify patients who are at a higher risk of progression, according to research published in the March issue of Cancer Prevention Research.

Abstract (http://cancerpreventionresearch.aacrjournals.org/content/6/3/196.abstract )Full Text (subscription or payment may be required) (http://cancerpreventionresearch.aacrjournals.org/content/6/3/196.full )

Coordinated Care Model Suggested for Palliative Care

THURSDAY, March 7 (HealthDay News) -- To deal with the increasing demand for palliative care services, a coordinated palliative care model is proposed, according to a perspective piece published online March 6 in the New England Journal of Medicine.

Full Text (http://www.nejm.org/doi/full/10.1056/NEJMp1215620?query=featured_home )

Lowering CT Tube Voltage for Colonography Beneficial

THURSDAY, March 7 (HealthDay News) -- In patients undergoing computed tomography (CT) colonography, reducing the tube voltage from 120 kVp to 100 kVp significantly reduces radiation dose while minimally reducing image quality, regardless of patient size, according to a study published in the March issue of Radiology.

Abstract (http://radiology.rsna.org/content/266/3/791.abstract )Full Text (subscription or payment may be required) (http://radiology.rsna.org/content/266/3/791.full )

Study Compares Procedures for Postmastectomy Reconstruction

WEDNESDAY, March 6 (HealthDay News) -- For patients undergoing autologous postmastectomy breast reconstruction, the rates of complications vary with different procedures, according to research published in the February issue of the Journal of the American College of Surgeons.

Abstract (http://www.journalacs.org/article/S1072-7515(12)01311-7/abstract )Full Text (subscription or payment may be required) (http://www.journalacs.org/article/S1072-7515(12)01311-7/fulltext )

Most Docs Report Information Overload in EHR-Setting

WEDNESDAY, March 6 (HealthDay News) -- Primary care practitioners (PCPs) using electronic health records (EHRs) are susceptible to information overload and feel that the EHR notification system makes it possible to miss test results, according to a research letter published online March 4 in JAMA Internal Medicine.

Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657753 )

First Causal Evidence of Visceral Fat-Cancer Connection

WEDNESDAY, March 6 (HealthDay News) -- Reduction of visceral fat through surgery or diet reduces intestinal tumors in mice, with clear differences between males and females, according to a study published in the March issue of Cancer Prevention Research.

Abstract (http://cancerpreventionresearch.aacrjournals.org/content/6/3/177.abstract )Full Text (http://cancerpreventionresearch.aacrjournals.org/content/6/3/177.full )

Clinical Trials Published Almost Two Years After Completion

WEDNESDAY, March 6 (HealthDay News) -- Clinical trials are published, on average, almost two years after completion, with time to publication affected by the funding source, number of trial participants, and journal impact factor, according to a research letter published online March 4 in JAMA Internal Medicine.

Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1657754 )

Low-Risk Bladder Cancer Rarely Progresses to Muscle Invasion

TUESDAY, March 5 (HealthDay News) -- Low-risk bladder cancer rarely progresses to muscle invasion but is associated with an increased risk of disease-specific mortality compared with matched populations, according to research published in the March issue of The Journal of Urology.

Abstract (http://www.jurology.com/article/S0022-5347(12)04977-4/abstract )Full Text (subscription or payment may be required) (http://www.jurology.com/article/S0022-5347(12)04977-4/fulltext )

Risk-Based Chemo Is Effective for Retinoblastoma

TUESDAY, March 5 (HealthDay News) -- Risk classification based on histopathologic features is an effective approach to selecting appropriate adjuvant therapy for patients with intraocular unilateral retinoblastoma treated by primary enucleation, according to a study published online March 5 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.42.3962.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/03/04/JCO.2012.42.3962.full.pdf+html )

U.K. Health Performance Worse Than Comparable Countries

TUESDAY, March 5 (HealthDay News) -- The United Kingdom has worse health performance than other comparable countries, according to a study published online March 5 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60355-4/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60355-4/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)60188-9/fulltext )

Diagnostic Testing Does Little to Reassure Patients

TUESDAY, March 5 (HealthDay News) -- Although further primary care visits may be reduced, diagnostic tests for symptoms with a low risk of serious illness actually do little to reassure patients, decrease their anxiety, or resolve their symptoms over the short or long term, according to research published online Feb. 25 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1656539#Abstract )Full Text (subscription or payment may be required) (http://store.jamanetwork.com/productDetails.aspx?articleid=1656539 )

Proportion of Black Males in U.S. Medical Schools Dropping

MONDAY, March 4 (HealthDay News) -- The proportion of black males in medical school is decreasing, according to a report published by the Association of American Medical Colleges (AAMC).

More Information (https://www.aamc.org/initiatives/diversity/179816/facts_and_figures.html )

Panel Recommends 10 Patient Safety Strategies

MONDAY, March 4 (HealthDay News) -- An expert panel is strongly encouraging the immediate adoption of 10 patient safety strategies and encouraging the adoption of a further 12, according to a supplement published in the March 5 issue of the Annals of Internal Medicine.

Full Text (http://annals.org/article.aspx?articleid=1657884 )Editorial (http://annals.org/article.aspx?articleid=1656416 )

Screening May Reduce Risk for Late-Stage CRC by 70 Percent

MONDAY, March 4 (HealthDay News) -- For average-risk adults, screening colonoscopy is associated with a significant decrease in the risk of any colorectal cancer (CRC) and of right colon cancer; and interventions using electronic health records (EHRs) increase screening rates, according to two studies published in the March 5 issue of the Annals of Internal Medicine.

Full Text - Doubeni (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1656410 )Full Text - Green (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1656409 )

Computerized Provider Order Entry System Cuts Rx Errors

MONDAY, March 4 (HealthDay News) -- Electronic prescribing through computerized provider order entry (CPOE) systems can substantially reduce medication errors in inpatient acute-care settings, according to a study published online Feb. 20 in the Journal of the American Medical Informatics Association.

Abstract (http://jamia.bmj.com/content/early/2013/01/27/amiajnl-2012-001241.short )Full Text (http://jamia.bmj.com/content/early/2013/01/27/amiajnl-2012-001241.full )

CMS Reports on Progress Toward Improved Health Care

MONDAY, March 4 (HealthDay News) -- Considerable progress has already been made toward improving the quality and delivery of health care, according to a Centers for Medicare and Medicaid Services (CMS) bulletin published online Feb. 28.

More Information (http://content.govdelivery.com/bulletins/gd/USCMS-6e809e )

Personalized Patient-Risk Info Enhances Informed Choice

FRIDAY, March 1 (HealthDay News) -- When patients are given personalized versus generic risk information, they are better able to make genuinely informed choices about undergoing screening tests, according to research published online Feb. 28 in The Cochrane Library.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001865.pub3/abstract;jsessionid=94CDF1CD396A27209DECE166FF170214.d03t02 )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001865.pub3/full )

Sequestration to Impact Health Care-Related Programs

FRIDAY, March 1 (HealthDay News) -- The $85 billion of mandatory cuts in federal spending that take effect March 1 as part of sequestration will be felt across health care and related programs, with cuts to Medicare providers and to the budgets of federal agencies.

More Information (http://www.cms.gov/ )

Ocular Complications Common After Pediatric HSCT

FRIDAY, Mar. 1 (HealthDay News) -- For pediatric patients undergoing hematopoietic stem cell transplantation (HSCT), complications are common, but are generally mild and self-limiting, according to a study published online Feb. 28 in JAMA Ophthalmology.

Abstract (http://archopht.jamanetwork.com/article.aspx?articleid=1656352#Abstract )Full Text (subscription or payment may be required) (http://archopht.jamanetwork.com/article.aspx?articleid=1656352 )