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August 2013 Briefing - Neurology

August 2013 Briefing - Neurology

Here are what the editors at HealthDay consider to be the most important developments in Neurology for August 2013. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Statins Appear to Benefit Elderly Without Previous CVD

FRIDAY, Aug. 30 (HealthDay News) -- Statins significantly reduce the incidence of myocardial infarction (MI) and stroke among elderly subjects without established cardiovascular (CV) disease, but do not significantly prolong survival in the short term, according to a review published online Aug. 28 in the Journal of the American College of Cardiology.

Full Text (subscription or payment may be required) (http://content.onlinejacc.org/article.aspx?articleid=1732396 )Editorial (subscription or payment may be required) (http://content.onlinejacc.org/article.aspx?articleid=1732395 )

FDA Investigating PML in Patient Taking MS Drug

FRIDAY, Aug. 30 (HealthDay News) -- The U.S. Food and Drug Administration is investigating the possible association between a rare brain infection and the multiple sclerosis (MS) drug Gilenya (fingolimod), according to a drug safety alert issued by the agency.

More Information (http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm366751.htm )

Comprehensive Stroke System Key to Reducing Death

FRIDAY, Aug. 30 (HealthDay News) -- A comprehensive stroke care system that addresses patient needs from symptom onset through rehabilitation can reduce stroke-related death and disability, according to an American Heart Association/American Stroke Association policy statement published online Aug. 29 in Stroke.

Full Text (http://stroke.ahajournals.org/content/early/2013/08/29/STR.0b013e3182a6d2b2.full.pdf+html )

Biomarkers Lower in Patients With Early Parkinson's Disease

THURSDAY, Aug. 29 (HealthDay News) -- Four biomarkers are found at lower levels in the cerebrospinal fluid of patients with early Parkinson's disease and are correlated with greater motor severity and a particular motor phenotype, according to a study published online Aug. 26 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1729660#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1729660 )

Structural Brain Changes More Common in Migraineurs

THURSDAY, Aug. 29 (HealthDay News) -- Structural brain changes seem to be more common for migraineurs, and the incidence rate of migraine is inversely related to household income, according to research published online Aug. 28 and 29 in Neurology.

Abstract - Bashir (http://www.neurology.org/content/early/2013/08/28/WNL.0b013e3182a6cb32.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2013/08/28/WNL.0b013e3182a6cb32.full.pdf+html )Abstract - Stewart (http://www.neurology.org/content/early/2013/08/29/WNL.0b013e3182a43b32.short )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2013/08/29/WNL.0b013e3182a43b32.full.pdf+html )Editorial (subscription or payment may be required) (http://www.neurology.org/content/early/2013/08/29/WNL.0b013e3182a43ea7.short )

Model of Brain Illustrates Development and Disease

THURSDAY, Aug. 29 (HealthDay News) -- A three-dimensional model of the brain derived from cultured cells recapitulates the organization and development of the brain and has been used to identify a defect in microcephaly, a disorder that has been difficult to model in mice, according to a study published online Aug. 28 in Nature.

Abstract (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12517.html )Full Text (subscription or payment may be required) (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12517.html#access )

Enzymes Key to Expression of Genes Linked to Autism

THURSDAY, Aug. 29 (HealthDay News) -- A class of enzymes called topoisomerases is important for the expression of very long genes, which are common among genes linked to autism spectrum disorder (ASD), according to a study published online Aug. 28 in Nature.

Abstract (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12504.html )Full Text (subscription or payment may be required) (http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12504.html#access )

Final Rules Issued for Individual Shared Responsibility Mandate

WEDNESDAY, Aug. 28 (HealthDay News) -- Starting 2014, the individual shared responsibility provision of the Affordable Care Act, which calls for each individual to have basic health insurance coverage, will be implemented, according to a statement from the U.S. Department of the Treasury.

More Information (http://www.treasury.gov/press-center/press-releases/Pages/jl2152.aspx )

Health Care Savings With Early Accountable Care Organizations

WEDNESDAY, Aug. 28 (HealthDay News) -- Early accountable care organization initiatives correlate with lower spending for elderly Medicare beneficiaries, but not necessarily with improved quality, according to a study published in the Aug. 28 issue of the Journal of the American Medical Association.

Abstract (http://jama.jamanetwork.com/article.aspx?articleid=1733718#Abstract )Full Text (subscription of payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1733718 )

Long Runs of Homozygosity Linked to Alzheimer's Disease

TUESDAY, Aug. 27 (HealthDay News) -- For Hispanic individuals, the mean length of runs of homozygosity (ROHs) is greater for those with Alzheimer's disease (AD), particularly familial AD, than for controls, according to research published online Aug. 26 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1729659#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1729659 )

Early Auditory Learning May Begin in the Womb

MONDAY, Aug. 26 (HealthDay News) -- The brain is capable of auditory learning before birth, which may have implications for language acquisition and disorders such as dyslexia, according to a study published online Aug. 26 in the Proceedings of the National Academy of Sciences.

Abstract (http://www.pnas.org/content/early/2013/08/14/1302159110.abstract )Full Text (subscription or payment may be required) (http://www.pnas.org/content/early/2013/08/14/1302159110.full.pdf+html )

Correct Dose of Anti-Clotting Rx in Elderly Continues to Elude

MONDAY, Aug. 26 (HealthDay News) -- There are no differences in ischemic or bleeding outcomes with reduced-dose prasugrel versus clopidogrel in elderly patients with acute coronary syndromes (ACS), according to a study published in the Aug. 20 issue of Circulation.

Abstract (http://circ.ahajournals.org/content/128/8/823.abstract )Full Text (subscription or payment may be required) (http://circ.ahajournals.org/content/128/8/823.full )

Autistic Traits More Common in Children With ADHD

MONDAY, Aug. 26 (HealthDay News) -- About one in five children and adolescents with attention-deficit/hyperactivity disorder (ADHD) show signs of autism, according to a study published online Aug. 26 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/08/20/peds.2012-3947.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/08/20/peds.2012-3947.full.pdf+html )

tPA Use in Ischemic Stroke Nearly Doubled 2003 to 2011

FRIDAY, Aug. 23 (HealthDay News) -- The use of intravenous tissue plasminogen activator (IV tPA) in acute ischemic stroke (AIS) patients nearly doubled from 2003 to 2011, according to research published online Aug. 20 in Circulation: Cardiovascular Quality and Outcomes.

Abstract (http://circoutcomes.ahajournals.org/content/early/2013/08/20/CIRCOUTCOMES.111.000095.abstract )Full Text (subscription or payment may be required) (http://circoutcomes.ahajournals.org/content/early/2013/08/20/CIRCOUTCOMES.111.000095.full.pdf+html )

Smoking Affects Stroke Risk Similarly in Men, Women

FRIDAY, Aug. 23 (HealthDay News) -- The excess risk of stroke associated with smoking is not significantly different for men and women, according to a meta-analysis published online Aug. 22 in Stroke.

Abstract (http://stroke.ahajournals.org/content/early/2013/08/22/STROKEAHA.113.002342.abstract )Full Text (subscription or payment may be required) (http://stroke.ahajournals.org/content/early/2013/08/22/STROKEAHA.113.002342.full.pdf+html )

Children With Autism Favor Play With Sensory Component

FRIDAY, Aug. 23 (HealthDay News) -- Children with autism spectrum disorders (ASD) prefer activities with a strong sensory component or cause-effect results, and avoid activities involving pretend play or arts and crafts, according to a study published in the July issue of the North American Journal of Medicine and Science.

Abstract (http://najms.net/v06i03p128a/ )Full Text (subscription or payment may be required) (http://najms.net/v06i03p128a/ )

Improved Sleep May Improve Exercise Duration

FRIDAY, Aug. 23 (HealthDay News) -- The length of an individual's sleep appears to influence their participation level in exercise the next day, according to a small study published in the August issue of the Journal of Clinical Sleep Medicine.

Abstract (http://www.aasmnet.org/JCSM/ViewAbstract.aspx?pid=29078 )Full Text (subscription or payment may be required) (http://www.aasmnet.org/JCSM/ViewAbstract.aspx?pid=29078 )

Ultra-Early IV Thrombolysis Minimizes Stroke Disability

THURSDAY, Aug. 22 (HealthDay News) -- Ultra-early intravenous thrombolysis increases the likelihood of an excellent outcome in patients with moderate and mild stroke symptoms, according to research published online Aug. 22 in Stroke.

Abstract (http://stroke.ahajournals.org/content/early/2013/08/22/STROKEAHA.111.000819.abstract )Full Text (http://stroke.ahajournals.org/content/early/2013/08/22/STROKEAHA.111.000819.full.pdf+html )

Brain Atrophy Seen in Patients With Diabetes

THURSDAY, Aug. 22 (HealthDay News) -- Brain atrophy rather than cerebrovascular lesions may explain the relationship between type 2 diabetes mellitus (T2DM) and cognitive impairment, according to a study published online Aug. 12 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/08/06/dc13-0143.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/08/06/dc13-0143.full.pdf+html )

Pregnancy Linked to Sleep Apnea, Especially With GDM

THURSDAY, Aug. 22 (HealthDay News) -- Pregnancy is associated with sleep disturbances and with obstructive sleep apnea (OSA), especially in the presence of gestational diabetes mellitus (GDM), according to a study published online Aug. 21 in the Journal of Clinical Endocrinology & Metabolism.

Abstract (http://jcem.endojournals.org/content/early/2013/08/20/jc.2013-2348.abstract )Full Text (subscription or payment may be required) (http://jcem.endojournals.org/content/early/2013/08/20/jc.2013-2348.full.pdf+html )

Genetic Traits Tie Alcohol Dependence, Eating Disorders

WEDNESDAY, Aug. 21 (HealthDay News) -- Common genes may be responsible for alcohol dependence and eating disorders, according to a study published in the September issue of the Journal of Studies on Alcohol and Drugs.

Abstract (http://www.jsad.com/jsad/article/A_Twin_Study_of_Alcohol_Dependence_Binge_Eating_and_Compensatory_Behavior/4844.html )Full Text (http://www.jsad.com/jsad/downloadarticle/A_Twin_Study_of_Alcohol_Dependence_Binge_Eating_and_Compensatory_Behavior/5180.pdf )

Two Presentations for Chronic Traumatic Encephalopathy

WEDNESDAY, Aug. 21 (HealthDay News) -- Two distinct clinical patterns are seen in patients with chronic traumatic encephalopathy (CTE), according to a study published online Aug. 21 in Neurology.

Abstract (http://www.neurology.org/content/early/2013/08/21/WNL.0b013e3182a55f7f.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2013/08/21/WNL.0b013e3182a55f7f.full.pdf+html )

Decision Support System Improves ADHD Diagnosis

WEDNESDAY, Aug. 21 (HealthDay News) -- Use of a clinical decision support module results in higher quality of attention-deficit/hyperactivity disorder (ADHD) diagnosis, according to a study published online Aug. 19 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/08/13/peds.2013-0933.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/08/13/peds.2013-0933.full.pdf+html )

Haloperidol Has No Effect on Delirium in Critically Ill Patients

WEDNESDAY, Aug. 21 (HealthDay News) -- In critically ill patients requiring ventilation, haloperidol treatment does not affect the amount of time alive without delirium or coma compared with placebo, according to a study published online Aug. 21 in The Lancet Respiratory Medicine.

Abstract (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70166-8/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70166-8/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70178-4/fulltext )

CSF Markers Tied to Integrity of Brain Functional Network

WEDNESDAY, Aug. 21 (HealthDay News) -- Abnormal levels of cerebrospinal fluid biomarkers Aβ42 and phosphorylated tau181 are associated with decreased functional connectivity in the default mode network prior to clinical onset of Alzheimer's disease, according to a study published online Aug. 19 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1725717#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1725717 )Editorial (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1725716 )

Decreased Activation in Brain Networks Post-Concussion

WEDNESDAY, Aug. 21 (HealthDay News) -- Injured athletes show decreased activation of right hemisphere attentional networks in the post-concussion period, with hyperactivation seen at seven weeks post-injury, according to a study published in the September issue of the Journal of the International Neuropsychological Society.

Abstract (http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8952254 )Full Text (subscription or payment may be required) (http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8952254 )

Implications, Solutions for U.S. Health Disparities Discussed

TUESDAY, Aug. 20 (HealthDay News) -- Research on health disparities in the United States, the policy implications of these disparities, and suggestions for improvement of disparities are discussed in "Health Policy Brief: Health Gaps," published Aug. 15 in Health Affairs.

Full Text (http://www.healthaffairs.org/healthpolicybriefs/brief.php?brief_id=98 )

CDC Estimates 300,000 Cases of Lyme Disease in U.S./Year

TUESDAY, Aug. 20 (HealthDay News) -- An estimated 300,000 Americans are diagnosed with Lyme disease each year, according to a report presented at the 2013 International Conference on Lyme Borreliosis and Other Tick-Borne Diseases in Boston.

More Information (http://www.cdc.gov/media/releases/2013/p0819-lyme-disease.html )

Spinal Radiosurgery Ups Risk of Vertebral Fracture

TUESDAY, Aug. 20 (HealthDay News) -- Vertebral compression fracture (VCF) is a common adverse effect in patients receiving spine stereotactic body radiotherapy (SBRT), according to research published online Aug. 19 in the Journal of Clinical Oncology.

Abstract (http://jco.ascopubs.org/content/early/2013/08/19/JCO.2013.50.1411.abstract )Full Text (subscription or payment may be required) (http://jco.ascopubs.org/content/early/2013/08/19/JCO.2013.50.1411.full.pdf+html )

Increasing Operating Costs Top Concern for Medical Practices

TUESDAY, Aug. 20 (HealthDay News) -- The top five concerns of medical practice executives all relate to financial management, with dealing with increasing operating costs reported as the most difficult daily challenge, according to a report published by the Medical Group Management Association (MGMA).

More Information (http://www.mgma.com/press/default.aspx?id=1374836 )

Score Predicts 10-Year Risk of Dementia in Type 2 Diabetes

TUESDAY, Aug. 20 (HealthDay News) -- A risk score has been created and validated to predict the 10-year risk of dementia among patients with type 2 diabetes, according to a study published online Aug. 20 in The Lancet Diabetes & Endocrinology.

Abstract (http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70048-2/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70048-2/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70091-3/fulltext )

Expansion of Pharmacists' Practice Will Benefit Patients

MONDAY, Aug. 19 (HealthDay News) -- The expanding scope of pharmacists' practice will potentially improve patient care but has implications for physicians, according to an article published online Aug. 19 in CMAJ, the journal of the Canadian Medical Association.

Full Text (subscription or payment may be required) (http://www.cmaj.ca/content/early/2013/08/19/cmaj.121990 )

High-Altitude Pilots Have More White Matter Hyperintensities

MONDAY, Aug. 19 (HealthDay News) -- Pilots of U-2 high-altitude reconnaissance aircraft with occupational exposure to hypobaria show a significant increase in both the number of and volume of white matter hyperintensities (WMH), according to a study published in the Aug. 20 issue of Neurology.

Abstract (http://www.neurology.org/content/81/8/729.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/81/8/729.full )

Estimated Recurrence Risk for Autism Spectrum Disorders 6.9

MONDAY, Aug. 19 (HealthDay News) -- The overall relative recurrence risk for autism spectrum disorders (ASDs) is 6.9, with significant risks seen for maternal and paternal full-siblings and for maternal half-siblings, according to a study published online Aug. 19 in JAMA Pediatrics.

Abstract (http://archpedi.jamanetwork.com/article.aspx?articleid=1728998#Abstract )Full Text (subscription or payment may be required) (http://archpedi.jamanetwork.com/article.aspx?articleid=1728998 )

Study IDs Factors Linked to Delayed ASD Diagnosis in Latinos

MONDAY, Aug. 19 (HealthDay News) -- Delayed identification of autism spectrum disorder (ASD) in Latino children is due to multiple factors, including limited general developmental and ASD screening in Spanish, difficulties in assessing ASD risk in primarily Spanish-speaking families, and lack of access to developmental specialists, according to a study published online Aug. 19 in Pediatrics.

Abstract (http://pediatrics.aappublications.org/content/early/2013/08/13/peds.2013-0383.abstract )Full Text (subscription or payment may be required) (http://pediatrics.aappublications.org/content/early/2013/08/13/peds.2013-0383.full.pdf+html )

Some Neurologists Unaware of Epileptic Drug Risks

MONDAY, Aug. 19 (HealthDay News) -- About one in five neurologists in the United States are not aware of recent warnings from the U.S. Food and Drug Administration regarding anti-epileptic drugs, according to a study published in the October issue of Epilepsy & Behavior.

Full Text (http://www.sciencedirect.com/science/article/pii/S1525505013002862 )

HHS Awards $67 Million to Marketplace Navigators

MONDAY, Aug. 19 (HealthDay News) -- $67 million is being awarded to Navigator grant applicants and their staff, who will serve as an in-person resource for those requiring additional assistance in shopping for and enrolling in Health Insurance Marketplace plans, according to a report published by the U.S. Department of Health and Human Services.

More Information (http://www.hhs.gov/news/press/2013pres/08/20130815a.html )

Bloodspot-Based Biomarker Test Identifies Fibromyalgia

MONDAY, Aug. 19 (HealthDay News) -- A rapid biomarker-based method using blood samples is able to accurately differentiate patients with fibromyalgia syndrome (FM) from those with rheumatoid arthritis (RA) or osteoarthritis (OA), according to a study published in the Aug. 21 issue of Analyst.

Abstract (http://pubs.rsc.org/en/content/articlelanding/2013/an/c3an36615d )Full Text (subscription or payment may be required) (http://pubs.rsc.org/en/content/articlelanding/2013/an/c3an36615d )

FDA: Fluoroquinolones May Cause Irreversible Nerve Damage

FRIDAY, Aug. 16 (HealthDay News) -- Fluoroquinolone antibacterial drugs may cause permanent nerve damage; the U.S. Food and Drug Administration is requiring updated drug labels and medication guides to reflect this fact, according to a Drug Safety Communication issued by the agency.

More Information (http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm365302.htm?source=govdelivery )

IOM Describes Themes Relating to Patients' Role in Health Care

FRIDAY, Aug. 16 (HealthDay News) -- Themes and messages relating to the role of patients in informed care decisions, knowledge generation, and value improvement were discussed at the Institute of Medicine's (IOM) Workshop Proceedings, according to a report published Aug. 15 in conjunction with the transcript of the proceedings.

More Information (http://www.iom.edu/Reports/2013/Partnering-with-Patients-to-Drive-Shared-Decisions-Better-Value-and-Care-Improvement.aspx )

Depression Linked to Cognitive Decline in Type 2 Diabetes

THURSDAY, Aug. 15 (HealthDay News) -- For patients with type 2 diabetes, depression correlates with greater cognitive decline over 40-months of follow-up, according to a study published online Aug. 14 in JAMA Psychiatry.

Abstract (http://archpsyc.jamanetwork.com/article.aspx?articleid=1727436#Abstract )Full Text (subscription or payment may be required) (http://archpsyc.jamanetwork.com/article.aspx?articleid=1727436 )

Brain Region Linked to Reading Skills and Dyslexia

THURSDAY, Aug. 15 (HealthDay News) -- The size of a region of brain white matter known as the left arcuate fasciculus, which connects language regions of the brain, is associated with poor pre-reading skills in kindergarteners and an increased risk of dyslexia, according to a study published in the Aug. 14 issue of The Journal of Neuroscience.

Abstract (http://www.jneurosci.org/content/33/33/13251.abstract )Full Text (subscription or payment may be required) (http://www.jneurosci.org/content/33/33/13251.full )

Involved Patients Have Better Health Care Experiences

THURSDAY, Aug. 15 (HealthDay News) -- Health care providers and patients shape the care experience, and strategies to improve care interactions should also help patients ensure that their needs are met, according to research published in the July issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/7/1299.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/7/1299.full )

Doctors Pessimistic About Future of U.S. Health Care

THURSDAY, Aug. 15 (HealthDay News) -- Physicians report concerns regarding health care delivery and the future of health care, according to survey findings published by athenahealth.

More Information (http://investors.athenahealth.com/phoenix.zhtml?c=213592&p=irol-newsArticle&ID=1846875&highlight= )

Unresponsive Brain Damaged Patients Can Communicate

THURSDAY, Aug. 15 (HealthDay News) -- Patients who are nonresponsive due to severe brain injury can nevertheless selectively focus their attention to follow commands and communicate via a brain scan, according to a study published online Aug. 12 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1724990#Abstract )Full Text (http://archneur.jamanetwork.com/article.aspx?articleid=1724990 )Editorial (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1724987 )

MRI-Guided Ultrasound Surgery Beneficial for Essential Tremor

WEDNESDAY, Aug. 14 (HealthDay News) -- Patients with severe, medication-refractory essential tremor benefit from the use of transcranial magnetic resonance imaging (MRI)-guided focused ultrasound thalamotomy, according to a study published in the Aug. 15 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1300962 )

Vitamin D Doesn't Improve Blood Pressure in Elderly

WEDNESDAY, Aug. 14 (HealthDay News) -- Vitamin D supplementation does not improve blood pressure (BP) in older patients with isolated systolic hypertension, according to a study published online Aug. 12 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1726994#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1726994 )

Study Shows Dramatic Decline in Ischemic Stroke Incidence

WEDNESDAY, Aug. 14 (HealthDay News) -- In a Texas community, the incidence of ischemic stroke is declining, but an ethnic disparity exists, according to research published online Aug. 13 in the Annals of Neurology.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/ana.23972/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/ana.23972/full )

Medicare Reimbursement Drives Procedural Over Cognitive Care

WEDNESDAY, Aug. 14 (HealthDay News) -- Physicians treating Medicare patients are reimbursed three to five times more for performing common procedures versus providing cognitive care, according to a study published online Aug. 12 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1726999#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1726999 )

Physicians Should Consider Social Media As Public Space

WEDNESDAY, Aug. 14 (HealthDay News) -- A new approach is needed for resolving the physician online identity crisis, according to a viewpoint piece published in the Aug. 14 issue of the Journal of the American Medical Association.

Full Text (subscription or payment may be required) (http://jama.jamanetwork.com/article.aspx?articleid=1728725 )

Mediterranean Diet Reduces Stroke Risk in Some People

TUESDAY, Aug. 13 (HealthDay News) -- Among those with a particular genetic variant associated with an increased risk of type 2 diabetes, adherence to a Mediterranean diet reduces increased fasting glucose and lipids and reduces the risk of stroke, according to a study published online Aug. 13 in Diabetes Care.

Abstract (http://care.diabetesjournals.org/content/early/2013/08/06/dc13-0955.abstract )Full Text (subscription or payment may be required) (http://care.diabetesjournals.org/content/early/2013/08/06/dc13-0955.full.pdf+html )

New Initiative Announced for Patient-Doc Collaboration

TUESDAY, Aug. 13 (HealthDay News) -- A new Center for Patient Partnership in Healthcare (CPPH) has been launched to advance physician-patient collaboration, according to a report published by the American College of Physicians (ACP).

More Information (http://www.acponline.org/pressroom/cpph.htm?hp )

Nine Risk Factors Identified for Young-Onset Dementia

TUESDAY, Aug. 13 (HealthDay News) -- Nine risk factors have been identified for young-onset dementia (YOD; dementia diagnosed before the age of 65 years), which together account for 68 percent of the population-attributable risk for YOD, according to a study published online Aug. 12 in JAMA Internal Medicine.

Abstract (http://archinte.jamanetwork.com/article.aspx?articleid=1726998#Abstract )Full Text (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1726998 )Editorial (subscription or payment may be required) (http://archinte.jamanetwork.com/article.aspx?articleid=1726991 )

Perceived Doc Verbal Abuse Impairs Nurses' Work Attitude

TUESDAY, Aug. 13 (HealthDay News) -- For registered nurses (RNs), perceived verbal abuse by physicians correlates with less favorable work conditions and attitudes, according to a study published in Nursing Outlook.

Abstract (http://www.nursingoutlook.org/article/S0029-6554(13)00005-5/abstract )Full Text (subscription or payment may be required) (http://www.nursingoutlook.org/article/S0029-6554(13)00005-5/fulltext )

Research Supports Treadmill Training Post-Spinal Cord Injury

TUESDAY, Aug. 13 (HealthDay News) -- Treadmill training soon after spinal cord injury is effective in improving walking ability if spinal cord inflammation is also reduced, according to an animal study published in the Aug. 7 issue of The Journal of Neuroscience.

Abstract (http://www.jneurosci.org/content/33/32/13101.abstract )Full Text (subscription or payment may be required) (http://www.jneurosci.org/content/33/32/13101.full )

Retinal Imaging May Help Assess Risk of Stroke

MONDAY, Aug. 12 (HealthDay News) -- For adults with hypertension, the presence of hypertensive retinopathy is associated with long-term risk of stroke, even for those with good hypertension control, according to a study published online Aug. 12 in Hypertension.

Abstract (http://hyper.ahajournals.org/content/early/2013/08/12/HYPERTENSIONAHA.113.01414.abstract )Full Text (subscription or payment may be required) (http://hyper.ahajournals.org/content/early/2013/08/12/HYPERTENSIONAHA.113.01414.full.pdf+html )

U.S. Hospitals Up Exchange of Electronic Health Information

MONDAY, Aug. 12 (HealthDay News) -- Between 2008 and 2012, hospitals significantly increased their exchange of electronic health information with other providers, according to research published in the August issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/8/1346.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/8/1346.full )

Famous Faces Help Identify Young-Onset Dementia

MONDAY, Aug. 12 (HealthDay News) -- Patients with primary progressive aphasia, a type of young-onset clinical dementia, have difficulty naming and recognizing famous faces, which is associated with cortical atrophy in particular brain areas, according to a study published in the Aug. 13 issue of Neurology.

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Guidelines for Post-HIV Exposure Management Updated

MONDAY, Aug. 12 (HealthDay News) -- Management and prophylaxis recommendations have been updated for health care providers with occupational exposure to HIV, according to guidelines published in the September issue of Infection Control and Hospital Epidemiology.

Full Text (http://www.jstor.org/stable/10.1086/672271 )

ER Visits Related to Use of CNS Stimulants Up From '05 to '11

MONDAY, Aug. 12 (HealthDay News) -- From 2005 to 2011, the number of emergency department visits related to nonmedical use of central nervous system (CNS) stimulants increased about four-fold among 18- to 34-year-olds, according to a report published Aug. 8 by the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA).

More Information (http://www.samhsa.gov/data/spotlight/spot103-CNS-stimulants-adults.pdf )

Medical Center Farmers Market Aids in Medical Home Goals

MONDAY, Aug. 12 (HealthDay News) -- A seasonal farmers market at a medical center can support the institution's commitment to the goals of the medical home, according to a study published online Aug. 1 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

Full Text (http://www.cdc.gov/pcd/issues/2013/13_0105.htm )

Physicians' Malpractice Concerns Predict More Testing

FRIDAY, Aug. 9 (HealthDay News) -- Physicians' concerns about malpractice risk predict more aggressive diagnostic testing practices in office-based care, according to a study published in the August issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/8/1383.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/8/1383.full )

IPAs and PHOs Viable Option for Small Independent Practices

FRIDAY, Aug. 9 (HealthDay News) -- For small and medium-size independent practices, sharing care management and information technology resources with other practices through an independent practice association (IPA) or physician-hospital organization (PHO) is a viable alternative and may improve care for patients with chronic conditions, according to a study published in the August issue of Health Affairs.

Abstract (http://content.healthaffairs.org/content/32/8/1376.abstract )Full Text (subscription or payment may be required) (http://content.healthaffairs.org/content/32/8/1376.full )

Tool Developed for Predicting Delirium During Hospitalization

THURSDAY, Aug. 8 (HealthDay News) -- A tool has been developed and validated for predicting the likelihood of developing delirium during hospitalization, according to research published online Aug. 7 in the Journal of Hospital Medicine.

Abstract (http://onlinelibrary.wiley.com/doi/10.1002/jhm.2062/abstract )Full Text (subscription or payment may be required) (http://onlinelibrary.wiley.com/doi/10.1002/jhm.2062/full )

Cocoa Improves Neurovascular Coupling, Cognition in Elderly

WEDNESDAY, Aug. 7 (HealthDay News) -- Neurovascular coupling is significantly associated with cognitive function, and both are improved by cocoa consumption among elderly individuals with baseline impairments, according to a study published online Aug. 7 in Neurology.

Abstract (http://www.neurology.org/content/early/2013/08/07/WNL.0b013e3182a351aa.abstract )Full Text (subscription or payment may be required) (http://www.neurology.org/content/early/2013/08/07/WNL.0b013e3182a351aa.full.pdf+html )Editorial (subscription or payment may be required) (http://www.neurology.org/content/early/2013/08/07/WNL.0b013e3182a352b6.extract )

Higher Glucose Levels Linked to Increased Dementia Risk

WEDNESDAY, Aug. 7 (HealthDay News) -- For older adults with and without diabetes, higher glucose levels are associated with an increased risk of dementia, according to a study published in the Aug. 8 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required) (http://www.nejm.org/doi/full/10.1056/NEJMoa1215740?query=featured_home )

Self-Measured Monitoring Improves Blood Pressure

WEDNESDAY, Aug. 7 (HealthDay News) -- Self-measured blood pressure (SMBP) monitoring lowers BP in the short-term, according to a review published in the Aug. 6 issue of the Annals of Internal Medicine.

Full Text (subscription or payment may be required) (http://annals.org/article.aspx?articleid=1722499 )

AMA, AHA Call for Realignment of Meaningful Use Stage 2

WEDNESDAY, Aug. 7 (HealthDay News) -- The American Medical Association (AMA) and American Hospital Association (AHA) are calling for additional flexibility in the timing of the adoption of stage 2 meaningful use of electronic health records, according to a letter written to the U.S. Department of Health and Human Services (HHS).

More Information (http://www.amednews.com/article/20130805/government/130809987/1/ )

Meditation Reduces Smoking by 60 Percent

TUESDAY, Aug. 6 (HealthDay News) -- A few hours of meditation training improves self-control and reduces smoking by 60 percent, according to a study published online Aug. 5 in the Proceedings of the National Academy of Sciences.

Abstract (http://www.pnas.org/content/early/2013/07/31/1311887110.abstract )Full Text (http://www.pnas.org/content/early/2013/07/31/1311887110.full.pdf+html )

Primary Genes for Alzheimer's, Parkinson's Disease Risk Differ

TUESDAY, Aug. 6 (HealthDay News) -- A meta-analysis of genome-wide association studies suggests that the loci that confer increased risk for Alzheimer's disease and Parkinson's disease do not overlap; the results of the meta-analysis were published online Aug. 5 in JAMA Neurology.

Abstract (http://archneur.jamanetwork.com/article.aspx?articleid=1723187#Abstract )Full Text (subscription or payment may be required) (http://archneur.jamanetwork.com/article.aspx?articleid=1723187 )

Including Casinos in Smoke-Free Laws Cut Ambulance Calls

TUESDAY, Aug. 6 (HealthDay News) -- The extension of smoke-free laws to include casinos correlates with a significant decrease in the number of emergency calls originating from casinos, according to a study published online Aug. 5 in Circulation.

Abstract (http://circ.ahajournals.org/content/early/2013/08/02/CIRCULATIONAHA.113.003455.abstract )Full Text (http://circ.ahajournals.org/content/early/2013/08/02/CIRCULATIONAHA.113.003455.full.pdf+html )Editorial (http://circ.ahajournals.org/content/early/2013/08/02/CIRCULATIONAHA.113.004714.full.pdf+html )

Participation Increases in Online CME Activities

MONDAY, Aug. 5 (HealthDay News) -- The number of physicians and non-physicians participating in continuing medical education (CME) has increased, especially in online activities, according to a report published by the Accreditation Council for Continuing Medical Education (ACCME).

More Information (http://accme.org/sites/default/files/630_2012_Annual_Report_20130724_0.pdf )

Small-Fiber Polyneuropathy ID'd in Fibromyalgia Cases

MONDAY, Aug. 5 (HealthDay News) -- Some patients diagnosed with fibromyalgia may actually have small-fiber polyneuropathy (SFPN), according to a study published online June 7 in PAIN.

Abstract (http://www.painjournalonline.com/article/S0304-3959(13)00294-7/abstract )Full Text (subscription or payment may be required) (http://www.painjournalonline.com/article/S0304-3959(13)00294-7/fulltext )

Fighting-Related Injuries Harm Intelligence in Adolescents

FRIDAY, Aug. 2 (HealthDay News) -- Fighting-related injuries in adolescents are tied to subsequent negative impacts on cognitive function and intelligence, according to a study published online July 26 in the Journal of Adolescent Health.

Abstract (http://www.jahonline.org/article/S1054-139X(13)00333-9/abstract )Full Text (http://www.jahonline.org/article/S1054-139X(13)00333-9/fulltext )

Brain Chemical Changes Identify Children With Autism

FRIDAY, Aug. 2 (HealthDay News) -- Changes in the levels of certain chemicals in brain gray matter between 3 and 10 years of age can distinguish children with autism spectrum disorder from children with idiopathic developmental delay, according to a study published online July 31 in JAMA Psychiatry.

Abstract (http://archpsyc.jamanetwork.com/article.aspx?articleid=1722813 #Abstract )Full Text (subscription or payment may be required) (http://archpsyc.jamanetwork.com/article.aspx?articleid=1722813 )

Variable Blood Pressure Tied to Worse Cognitive Functioning

THURSDAY, Aug. 1 (HealthDay News) -- Higher visit-to-visit variability in blood pressure is associated with worse cognitive performance in older people at high risk of cardiovascular disease, according to a study published online July 30 in BMJ.

Full Text (http://www.bmj.com/content/347/bmj.f4600 )

Prevalence of Peripheral Artery Disease Increasing Globally

THURSDAY, Aug. 1 (HealthDay News) -- The prevalence of peripheral artery disease is increasing in both high-income countries (HIC) and low- or middle-income countries (LMIC), according to a review published online Aug. 1 in The Lancet.

Abstract (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61249-0/abstract )Full Text (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61249-0/fulltext )Editorial (subscription or payment may be required) (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61576-7/fulltext )

Immediate Post-Op Delirium Common in Elderly Patients

THURSDAY, Aug. 1 (HealthDay News) -- Delirium in the post-anesthesia care unit (PACU) is relatively common among elderly patients undergoing surgery with general anesthesia, according to a study published in the August issue of Anesthesia & Analgesia.

Abstract (http://www.anesthesia-analgesia.org/content/117/2/471.abstract )Full Text (http://www.anesthesia-analgesia.org/content/117/2/471.full )