Conditions InDepth: Congestive Heart Failure (CHF)
| Blood Flow Through the Heart |
![]() |
| Copyright © Nucleus Medical Media, Inc. |
- Left-sided failure: There are two main ways that the left ventricle can fail to keep up with the demands of the body. When the left ventricular muscle is damaged, it fails to contract/pump with sufficient force. That is called systolic failure. If the muscle is damaged in such a way that it becomes stiff and cannot accept all the blood it needs from the left atrium, then it is called diastolic failure. The difference between these two types of failure is important because the treatment approach for each type may be different. In either type, when the left ventricle fails to circulate the blood, the blood can “back up” into the lungs. Accumulation of fluid in the lungs causes one of the main symptoms of CHF, shortness of breath. Doctors use the term pulmonary edema to describe severe fluid build-up in the lungs.
- Right-sided failure: This occurs when the right ventricle fails to pump out enough blood to meet the body’s demand. In this case, the right ventricle and atrium cannot accept all the blood returning to the heart, and the blood “backs-up” into the veins and capillaries. The “overflow” of this fluid leaks out of the capillaries to the tissue, causing edema. Edema, or fluid accumulation, usually shows up as swelling, particularly in the legs. Right-sided failure usually occurs as a secondary result of left-sided failure, but it may also be caused by primary conditions that increase the pressure in the lungs.
| Pulmonary Edema |
![]() |
| Copyright © Nucleus Medical Media, Inc. |
- Hypertension (high blood pressure): If your arteries have become narrowed from fatty deposits or are less flexible due to aging or other causes, then your heart will have to pump much harder to get the blood through the arteries. This pumping effort is reflected in your “blood pressure.” If your heart muscle has to continually pump much harder than normal, then eventually, this may lead to heart muscle damage, and finally may cause heart failure.
- Coronary artery disease (CAD ): Cholesterol and fat can build up in the arteries that supply the heart with blood. This build-up narrows the blood vessels, causing reduced blood flow (ischemia) to the heart muscle, and an inability to meet increased blood flow demands (like from exercise). If the blood flow is completely cut off, a heart attack can occur. Heart attack means that an area of heart muscle has been deprived of blood and nutrients long enough that the area of heart muscle dies. If enough heart muscle is damaged in this way and the muscle cannot pump enough blood to meet the body’s needs, then heart failure occurs.
- Valvular heart disease: The four valves of the heart keep blood flowing efficiently and in the correct direction. If these valves become damaged or infected ( endocarditis ), the heart is forced to work harder. Over time, this can weaken the heart muscle.
- Cardiomyopathy: The heart may become damaged due to infection, chronic alcohol abuse, use of certain chemotherapy drugs, cocaine, or scarring from diseases. The damage results in inadequate contraction of the heart muscle, which can lead to CHF.
- Congenital heart defects: When there is a malformation of the heart muscle or valves at birth, the heart is forced to work harder to produce the same output. Over time, this may cause CHF.
- Diabetes : People who have diabetes are at increased risk of developing heart disease. They often have other conditions that increase their risk of heart disease, like high cholesterol and increased weight.
- Abnormal heart rhythms (arrhythmia): If a heart beats too slowly (bradycardia), the heart may not be able to pump out an adequate supply of blood. If the heart beats too quickly (tachycardia), there may not be enough time for the heart to fill with blood. Both of these conditions produce strain and may lead to CHF.
- Hyperthyroidism : This condition, caused by an overactive thyroid gland, increases the metabolic rate in the body. The increased levels of thyroid hormone signal the heart to pump faster and harder to supply the body with blood, causing strain, which (if uncorrected) may lead to CHF.
- Anemia : Red blood cells carry oxygen throughout the body. When the number of red blood cells is reduced ( anemia ), the heart must circulate blood more frequently to supply enough oxygen to the tissues. This is another type of strain that may lead to CHF.
References
American Heart Association website. Available at: http://www.americanheart.org/ .
Felker CM, Thompson RE, Hare JM, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med. 2000;342:1077.
He, J, Ogden, LG, Bazzano, LA, et al. Risk factors for congestive heart failure in US men and women: NHANES I epidemiologic follow-up study. Arch Intern Med. 2001;161:996.
National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/ .
Mayo Clinic Heart Center http://www.mayoclinic.com/health/heart-failure/HB00061 Last accessed at January 30, 2007
Revision Information
- Reviewer: Michael J. Fucci, DO
- Review Date: 09/2012 -
- Update Date: 00/91/2012 -

